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This page was prepared by Lynn Kash, RN, Internet Nursing Guide
Pennsylvania Nurses,Emergency Department
http://www.emergencyroomnursing.com/

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This drug is also known as: Trecator SC, Ethide, Ethiocid, Ethomid, Etomide, Mycotuf, Myobid.

Ethionamide (Trecator SC), Managing side effects, The Access Project:"Taking an antiemetic before treatment can help decrease or prevent gastrointestinal side effects. Antiemetics prevent or relieve symptoms of nausea and vomiting. Compazine and Dramamine are antiemetics. There are others. Your doctor will prescribe the best one for you."
AIDS Treatment Data Network
611 Broadway, Suite 613, New York, New York, 10012
Tel: 212-260-8868 / 800-734-7104 (NYS only) Fax: 212-260-8869
http://www.atdn.org/access/index.html

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Ethionamide, What side effects should I watch for, Drug Digest.org:"Nausea, vomiting, abdominal pain, diarrhea, drowsiness, dizziness or metallic taste might occur. If these persist or worsen, notify your doctor promptly. Changing the time of the dosage may relieve some side effects. Unlikely but report promptly any depression. Very unlikely but report promptly numbness or tingling of the hands and feet, seizures, shakiness, hallucinations, vision problems, yellowing of the eyes or skin, rash, mouth sores, sun sensitivity ("sunburn") or unusual bruising. Diabetics should also monitor more closely for low blood sugar symptoms."
Expresscripts.com
Burstyn, Lance
521 Alton Rd #208, Miami Beach, FL 33140, US
http://www.drugdigest.org/

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Trecator-SC, Possible side effects, Drugstore.com:"SIDE EFFECTS, that may go away during treatment, include nausea, vomiting, abdominal pain, excessive saliva, or metallic taste. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR AS SOON AS POSSIBLE if you experience any change in your vision, change in your sense of smell, or tingling of hands or feet. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist."
DrugStore.com
407 Heron Drive, Swedesboro, NJ 08085-9810
1-800-378-4786
http://www.drugstore.com/

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Ethionamide, What happens if I miss a dose, LaurusHealth.com:"Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication."
VHA Inc.
220 East Las Colinas Blvd. MIS, Irving, TX 75039-5500 US
HealthInfo@VHA.com
http://www.laurushealth.com/

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Ethionamide(Systemic), Pregnancy, Medformation.com:"Ethionamide causes birth defects in rats and rabbits given doses greater than the usual human dose. However, women with tuberculosis (TB) should be treated with medicines to treat TB. If you have any concerns, talk to your doctor.

Breast-feeding-It is not known whether ethionamide passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor."
ALLINA HEALTH SYSTEM
1375 WILLOW ST, MINNEAPOLIS, MN 55403-2252 US
612 775 1253 fax: 612 775 1249
http://www.medformation.com/

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Ethionamide (Systemic), Pregnancy, MEDLINEplus:"Ethionamide causes birth defects in rats and rabbits given doses greater than the usual human dose. However, women with tuberculosis (TB) should be treated with medicines to treat TB. If you have any concerns, talk to your doctor.

Breast-feeding-It is not known whether ethionamide passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor."
Office of Communications and Public Liaison
National Library of Medicine
8600 Rockville Pike Bethesda, Maryland 20894
Phone: (301) 496-6308 Fax: (301) 496-4450 email: publicinfo@nlm.nih.gov
http://www.nlm.nih.gov/medlineplus/

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Trecator, Common Uses, Mythos.com:"Ethionamide antimycobacterial (antituberculosis) used in combination with other drugs in the treatment of tuberculosis (TB). It is also effective for the treatment of MAC and may be used in combination with as many as 5 other drugs. MAC is related to TB, but no one TB drug works against MAC. TB is a disease caused by a bacterium that is spread through the air, usually when a person who has the disease coughs or sneezes. Anyone can become infected with TB bacteria, but people low resistance, including people with HIV/AIDS are at greater risk of catching TB. Although TB can occur any place in the body, only TB disease in the lungs (pulmonary TB) or throat is contagious. TB disease can be treated and cured with medication."
Mythos Software Corporation
4625 S Ash, Bldg J-1, Tempe, AZ 85282, US
http://www.mythos.com/pharmacy/

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Ethionamide, Indications, RxList.com:"Trecator-SC (ethionamide) is primarily indicated for the treatment of active tuberculosis in patients with M. tuberculosis resistant to isoniazid or rifampin, or when there is intolerance on the part of the patient to other drugs. Its use alone in the treatment of tuberculosis results in the rapid development of resistance. It is essential, therefore, to give a suitable companion drug or drugs, the choice being based on the results of susceptibility tests. If the susceptibility tests indicate that the patient's organism is resistant to one of the first-line antituberculosis drugs (i.e., isoniazid or rifampin) yet susceptible to ethionamide, ethionamide should be accompanied by at least one drug to which the M. tuberculosis isolate is known to be susceptible. 6 If the tuberculosis is resistant to both isoniazid and rifampin, yet susceptible to ethionamide, ethionamide should be accompanied by at least two other drugs to which the M. tuberculosis isolate is known to be susceptible.

Patient nonadherence to prescribed treatment can result in treatment failure and in the development of drug-resistant tuberculosis, which can be life-threatening and lead to other serious health risks. It is, therefore, essential that patients adhere to the drug regimen for the full duration of treatment. Directly observed therapy is recommended for all patients receiving treatment for tuberculosis. Patients in whom drug-resistant M. tuberculosis organisms are isolated should be managed in consultation with an expert in the treatment of drug-resistant tuberculosis."
RxList - The Internet Drug Index: Searchable drug database. RxList LLC
500 3rd Street Suite 530
San Francisco, CA 94107
707-747-0985 fax: 708 575 8638,info@rxlist.com
http://www.rxlist.com/

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Ethionamide, What other drugs will affect ethionamide, Web Md Health:"The risk of seizures may be increased when ethionamide is used in combination with cycloserine (Seromycin) or isoniazid (Nydrazid). Special monitoring may be necessary if you are taking a combination of these medicines.

Drugs other than those listed here may also interact with ethionamide. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines."
WebMD
1175 Peachtree Road, NE, Suite 2400, Atlanta, GA 30361.
212-624-3700service@webmd.net
http://my.webmd.com/content/drugs/

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Etionamide (Systemic), Proper Use of This Medicine, Yahoo Health:"Ethionamide may be taken with or after meals if it upsets your stomach.

To help clear up your tuberculosis (TB) completely, it is very important that you keep taking this medicine for the full time of treatment, even if you begin to feel better after a few weeks. You may have to take it every day for 1 to 2 years or more. It is important that you do not miss any doses.

Your doctor may also want you to take pyridoxine (e.g., Hexa-Betalin; vitamin B 6) every day to help prevent or lessen some of the side effects of ethionamide. If so, it is very important to take pyridoxine every day along with this medicine. Do not miss any doses."
Yahoo! Inc.
701 First Avenue, Sunnyvale, California 94089
Phone (408) 349-3300 Fax (408) 349-3301
http://www.yahoo.com/

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